验证数据展示
产品信息
16315-1-PBS targets PXK in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag9362 Product name: Recombinant human PXK protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-352 aa of BC014479 Sequence: MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALLIRMFNEKGTLKDLIYKAKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLDGDTCRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPD 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | PX domain containing serine/threonine kinase |
| 别名 | PX domain-containing protein kinase-like protein, MONaKA, Modulator of Na,K-ATPase, Modulator of Na,K ATPase |
| 计算分子量 | 450aa,52 kDa; 578aa,65 kDa |
| 观测分子量 | 55 kDa |
| GenBank蛋白编号 | BC014479 |
| 基因名称 | PXK |
| Gene ID (NCBI) | 54899 |
| RRID | AB_3669237 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q7Z7A4 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PXK is part of the sorting nexin (SNX) family of proteins, which are important for receptor internalization, organelle trafficking including endosomal trafficking, and other membrane-centric sorting functions. This is accomplished primarily through the PX-domain mediated binding of PI3P . PXK was first identified and cloned by two independent groups in 2005. Initial studies established that PXK is detectable in most tissues with a primarily cytoplasmic distribution. (PMID: 25620976)
