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验证数据展示

  • WB analysis using 28151-1-AP

    WB analysis using 28151-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 28151-1-AP (PTPRK antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

PTPRK Polyclonal antibody

PTPRK Polyclonal Antibody for WB, ELISA
Cat No. 28151-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

Human, mouse, rat

应用

WB, ELISA

别名

DKFZp686C2268, DKFZp779N1045, PTPK, PTPRK, R PTP kappa

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inmouse spleen tissue, rat spleen tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

28151-1-AP targets PTPRK in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 Human, mouse, rat
免疫原 PTPRK fusion protein Ag27765 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 protein tyrosine phosphatase, receptor type, K
别名 DKFZp686C2268, DKFZp779N1045, PTPK, PTPRK, R PTP kappa
计算分子量 1439 aa, 162 kDa
观测分子量 100-120 kDa
GenBank蛋白编号BC140775
基因名称 PTPRK
Gene ID (NCBI) 5796
RRIDAB_2881074
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ15262
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PTPRK (Protein Tyrosine Phosphatase Receptor Type Kappa), a member of the receptor-type protein tyrosine phosphatase family, is a transmembrane protein that regulates cell-cell contact. PTPRK is a 210 kDa precursor protein and converted by furin to a mature heterodimeric protein composed of a non-covalently attached amino-terminal extracellular subunit (E-subunit, 120 kDa) and carboxyl-terminal transmembrane subunit (P-subunit, 95 kDa) (PMID: 24882578, 16648485). Loss of PTPRK activity has been observed in pancreatic cancer, primary CNS lymphoma and melanoma, and is associated with poor survival of cancer patients, which suggest that PTPRK is a potential tumor suppressor (PMID: 23696788).

实验方案

Product Specific Protocols
WB protocol for PTPRK antibody 28151-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols