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验证数据展示

  • IP experiment of Jurkat using 31494-1-AP (same clone as 31494-1-PBS)

    IP experiment of Jurkat using 31494-1-AP (same clone as 31494-1-PBS)

    IP result of anti-C13orf23 (IP:31494-1-AP, 4ug; Detection:31494-1-AP 1:500) with Jurkat cells lysate 1800 ug. This data was developed using the same antibody clone with 31494-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary tumor using 31494-1-AP (same clone as 31494-1-PBS)

    IHC staining of human ovary tumor using 31494-1-AP (same clone as 31494-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 31494-1-AP (C13orf23 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31494-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 31494-1-AP (same clone as 31494-1-PBS)

    IF Staining of U2OS using 31494-1-AP (same clone as 31494-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using PROSER1 antibody (31494-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 31494-1-PBS in a different storage buffer formulation.

PROSER1 Polyclonal antibody, PBS Only

PROSER1 Polyclonal Antibody for IHC, IF/ICC, IP, Indirect ELISA
Cat No. 31494-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, IF/ICC, IP, Indirect ELISA

别名

C13orf23, bA50D16.2, KIAA2032, Proline And Serine Rich 1, Proline and serine-rich protein 1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

31494-1-PBS targets PROSER1 in IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag35678

Product name: Recombinant human C13orf23 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-178 aa of NM_025138.4

Sequence: MDKKSFEMVLDEIRKAVLTEYKLKAIEYVHGYFSSEQVVDLLRYFSWAEPQLKAMKALQHKMVAVQPTEVVNILNCFTFSKDKLVALELLASNIIDAQNSRPIEDLFRVNMSEKKRCKRILEQAFKGGCKAPHAMISSCGTIPGNPYPKGRPSRINGIFPGTPLKKDGEECTNEGKGI

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chromosome 13 open reading frame 23
别名 C13orf23, bA50D16.2, KIAA2032, Proline And Serine Rich 1, Proline and serine-rich protein 1
计算分子量96kDa，944aa
观测分子量100 kDa
GenBank蛋白编号NM_025138.4
基因名称 C13orf23
Gene ID (NCBI) 80209
RRIDAB_3742438
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ86XN7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PROSER1 (proline- and serine-rich 1) is a chromatin-binding protein encoded by the 13q13.3 locus. It interacts with all three TET enzymes and serves as the core scaffold of the TOPD (TET‑OGT‑PROSER1‑DBHS) complex, stabilizing the binding between TET2 and OGT while promoting O‑GlcNAcylation, thereby enhancing DNA demethylation activity. PROSER1 has recently been found to be associated with neurodevelopmental disorders.

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