• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • IF Staining of HeLa using CL488-84491-6

    IF Staining of HeLa using CL488-84491-6

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite® Plus 488 PQBP1 antibody (CL488-84491-6, Clone: 241901B11 ) at dilution of 1:200, CL594-Phalloidin (red).

CoraLite® Plus 488-conjugated PQBP1 Recombinant antibody

PQBP1 Uni-rAbTM Recombinant Antibody for IF/ICC
Cat No. CL488-84491-6

产品说明书

CloneNo. 241901B11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IF/ICC

别名

241901B11, Npw38, Polyglutamine tract-binding protein 1, Polyglutamine-binding protein 1, PQBP-1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格价格库存

点击咨询售前客服

点击咨询售后客服

经过测试的应用

Positive IF/ICC detected inHeLa cells
Planning an IHC experiment? We recommend our IHCeasy PQBP1 Ready-To-Use IHC Kit. PQBP1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 84491-6-PBS

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-84491-6 targets PQBP1 in applications and shows reactivity with human samples.

经测试应用 IF/ICC Application Description
经测试反应性 human
免疫原 PQBP1 fusion protein Ag9329 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 polyglutamine binding protein 1
别名 241901B11, Npw38, Polyglutamine tract-binding protein 1, Polyglutamine-binding protein 1, PQBP-1
计算分子量 265 aa, 30 kDa
观测分子量 30-32 kDa
GenBank蛋白编号BC012358
基因名称 PQBP1
Gene ID (NCBI) 10084
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO60828
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PQBP1 (Polyglutamine-binding protein 1) is also named as NPW38 and JM26. PQBP1 senses extrinsic tau 3R/4R proteins by direct interaction and triggers an innate immune response by activating a cyclic GMP-AMP synthase (cGAS)-Stimulator of interferon genes (STING) pathway (PMID: 34782623).  PQBP1 is abundantly expressed in the central nervous system during development. PQBP1 is a component of the precatalytic spliceosome (B complex) that is involved in splicing. PQBP1 was predominantly localized in the cell nucleus. PQBP1 is overexpressed in various cancer types including breast cancer, colon cancer, and glioblastoma (PMID: 38342602).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 PQBP1 antibody CL488-84491-6Download protocol
Standard Protocols
Click here to view our Standard Protocols