PPP3CA Monoclonal antibody

PPP3CA Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, Rat, Mouse, Rabbit, Pig

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2A5C1

Cat No : 68163-1-Ig

Print datasheet

Synonyms

CALN, CALNA, CALNA1, CAM PRP catalytic subunit, CCN1, CNA, CNA1, PPP2B, PPP3CA



经过测试的应用

Positive WB detected inSH-SY5Y cells, rabbit skeletal muscle tissue, pig brain tissue, rabbit brain tissue, rat brain tissue, mouse brain tissue, rat skeletal muscle

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

68163-1-Ig targets PPP3CA in WB, ELISA applications and shows reactivity with Human, Rat, Mouse, Rabbit, Pig samples.

Tested Applications WB, ELISA
Tested Reactivity Human, Rat, Mouse, Rabbit, Pig
Immunogen PPP3CA fusion protein Ag32642 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform
Synonyms CALN, CALNA, CALNA1, CAM PRP catalytic subunit, CCN1, CNA, CNA1, PPP2B, PPP3CA
Calculated Molecular Weight 59 kDa
Observed Molecular Weight59 kDa
GenBank Accession NumberBC025714
Gene Symbol PPP3CA
Gene ID (NCBI) 5530
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ08209
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PPP3CA, also called calcineurin Aα, is the only serine/threonine protein phosphatase under the control of Ca2+/calmodulin, and plays a critical role in the coupling of Ca2+ signals to cellular responses. Ca2+ signaling plays a central role in hypertrophic growth of cardiac and skeletal muscle in response to mechanical load and a variety of signals. Therefore, PPP3CA plays an important role in muscle differentiation, especially in muscle fiber type conversion. It is also involved in osteoclast regulation, regulating bone formation through an effect on osteoblast differentiation.

实验方案

Product Specific Protocols
WB protocol for PPP3CA antibody 68163-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols