验证数据展示
产品信息
55389-1-PBS targets PPP1R3G in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | protein phosphatase 1, regulatory (inhibitor) subunit 3G |
| 别名 | Protein phosphatase 1 regulatory subunit 3G |
| 计算分子量 | 38 kDa |
| 观测分子量 | 38-40 kDa |
| GenBank蛋白编号 | NM_001145115 |
| 基因名称 | PPP1R3G |
| Gene ID (NCBI) | 648791 |
| RRID | AB_3743208 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | B7ZBB8 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PPP1R3G (protein phosphatase 1 regulatory subunit 3G) is an important member of phosphatase 1 inhibitor -3 family, which is mainly expressed in liver and muscle and participates in glycogen synthesis and metabolism, insulin signaling pathway and lipid metabolism. PPP1R3G is the direct target of insulin -AKT signaling pathway. Insulin phosphorylates Ser79 site of PPP1R3G through AKT, which promotes its binding with GS, so that GS is dephosphorylated by PP1, thus enhancing glycogen synthesis.
