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验证数据展示

  • IHC staining of mouse cerebellum using 27787-1-AP (same clone as 27787-1-PBS)

    IHC staining of mouse cerebellum using 27787-1-AP (same clone as 27787-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 27787-1-AP (PNPLA7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27787-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse cerebellum using 27787-1-AP (same clone as 27787-1-PBS)

    IHC staining of mouse cerebellum using 27787-1-AP (same clone as 27787-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 27787-1-AP (PNPLA7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27787-1-PBS in a different storage buffer formulation.

PNPLA7 Polyclonal antibody, PBS Only

PNPLA7 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 27787-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

C9orf111, NTE R1, NTEL1, RP11 48C7.2

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

27787-1-PBS targets PNPLA7 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag27184

Product name: Recombinant human PNPLA7 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 302-468 aa of NM_001098537

Sequence: MVSVASVAAGKAKKQVFYGEEERLKKPPRLQESCDSDHGGGRPAAAGPLLKRSHSVPAPSIRKQILEELEKPGAGDPDPSAPQGGPGSATSDLGMACDRARVFLHSDEHPGSSVASKSRKSVMVAEIPSTVSQHSESHTDETLASRKSDAIFRAAKKDLLTLMKLEDS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 patatin-like phospholipase domain containing 7
别名 C9orf111, NTE R1, NTEL1, RP11 48C7.2
计算分子量 146 kDa
GenBank蛋白编号NM_001098537
基因名称 PNPLA7
Gene ID (NCBI) 375775
RRIDAB_3669623
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ6ZV29
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PNPLA7 (Patatin-like phospholipase domain-containing protein 7), also termed NTE-related 1 (NTE-R1) or NRE, is a member of the PNPLAs family, which is conserved protein in mice, rats and humans. It serves key roles in triglyceride hydrolysis, energy metabolism, lipid droplet (LD), and in regulation of adipocyte differentiation. It is reported that PNPLA7 was down-regulated in HCC through hypermethylation of its promoter, which indicates that PNPLA7 may be a potential biomarker for HCC diagnosis (PMID: 16799181, 27347198).

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