验证数据展示
产品信息
30905-1-PBS targets PNPLA1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag34139 Product name: Recombinant human PNPLA1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-59 aa of BC103907 Sequence: MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFV 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | patatin-like phospholipase domain containing 1 |
| 别名 | PNPLA 1, ARCI10 |
| 计算分子量 | 532 aa, 58 kDa |
| 观测分子量 | 48kDa;58kDa |
| GenBank蛋白编号 | BC103907 |
| 基因名称 | PNPLA1 |
| Gene ID (NCBI) | 285848 |
| RRID | AB_3669778 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q8N8W4 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PNPLA1 is a member of the patatin-like phospholipase (PNPLA) family. PNPLAs are highly conserved enzymes of prokaryotic and eukaryotic organisms that play an important role in lipid homeostasis. PNPLA1 has been identified as an essential transacylase for acylceramide biosynthesis to maintain the epidermal permeability barrier (PMID: 30290227). It is mainly expressed in the skin and has 3 isoforms with MW of 58, 48 and 49 kDa.
