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验证数据展示

  • WB analysis of Jurkat using 26916-1-AP

    WB analysis of Jurkat using 26916-1-AP

    WB result of PKC eta antibody (26916-1-AP; 1:1200; incubated at room temperature for 1.5 hours) with sh-Control and sh-PKC eta transfected Jurkat cells.

  • WB analysis using 26916-1-AP

    WB analysis using 26916-1-AP

    PC-3 cells were subjected to SDS PAGE followed by western blot with 26916-1-AP (PKC eta antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

  • KD/KO Validated

PKC eta Polyclonal antibody

PKC eta Polyclonal Antibody for WB, ELISA
Cat No. 26916-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

PRKCH, PKC L, PKCL, PRKCL, Protein kinase C eta type

缓冲液配方:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inPC-3 cells, Jurkat cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

26916-1-AP targets PKC eta in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag25365

Product name: Recombinant human PRKCH protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 634-683 aa of BC037268

Sequence: RIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 protein kinase C, eta
别名 PRKCH, PKC L, PKCL, PRKCL, Protein kinase C eta type
观测分子量75-90 kDa
GenBank蛋白编号BC037268
基因名称 PRKCH
Gene ID (NCBI) 5583
RRIDAB_3742204
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP24723
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PRKCH (gene ID: 5583) encodes protein kinase C eta (PKCη), a calcium‑independent, phospholipid‑dependent serine/threonine kinase of the novel PKC subfamily. It regulates cell proliferation, differentiation, and apoptosis, with prominent roles in keratinocyte differentiation, early B‑cell development, and epithelial barrier integrity. Genetic variants in PRKCH are linked to cerebral infarction and Alzheimer's disease, while PKCη exhibits context‑dependent functions in cancer-promoting progression and chemoresistance in some tumors (e.g., glioblastoma) but acting as a tumor suppressor in others (e.g., hepatocellular carcinoma).

实验方案

Product Specific Protocols
WB protocol for PKC eta antibody 26916-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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