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  • IHC staining of human placenta using 21169-1-AP (same clone as 21169-1-PBS)

    IHC staining of human placenta using 21169-1-AP (same clone as 21169-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 21169-1-AP (PITPNM2 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21169-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse placenta using 21169-1-AP (same clone as 21169-1-PBS)

    IHC staining of mouse placenta using 21169-1-AP (same clone as 21169-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse placenta tissue slide using 21169-1-AP (PITPNM2 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21169-1-PBS in a different storage buffer formulation.

PITPNM2/NIR3 Polyclonal antibody, PBS Only

PITPNM2/NIR3 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 21169-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

PITPNM2, KIAA1457, Membrane-associated phosphatidylinositol transfer protein 2, NIR3, NIR-3

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

21169-1-PBS targets PITPNM2/NIR3 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag15385

Product name: Recombinant human PITPNM2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 233-328 aa of BC141813

Sequence: EWYGLSMENIRELEKEAQLMLSRKMAQFNEDGEEATELVKHEAVSDQTSGEPPEPSSSNGEPLVGRGLKKQWSTSSKSSRSSKRGASPSRHSISEW

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 phosphatidylinositol transfer protein, membrane-associated 2
别名 PITPNM2, KIAA1457, Membrane-associated phosphatidylinositol transfer protein 2, NIR3, NIR-3
计算分子量 1349 aa, 149 kDa
GenBank蛋白编号BC141813
基因名称 PITPNM2
Gene ID (NCBI) 57605
RRIDAB_3742019
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BZ72
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PITPNM2, also known as NIR3, belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein(PMID: 15627748). PITPNM2/NIR3 promotes both TCRβ selection and positive selection in thymocytes. PITPNM2/NIR3 is required for PIP2 replenishment and TCR-induced calcium signaling in response to weak TCR stimulation(PMID: 36581712).

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