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验证数据展示

  • WB analysis of human urine using 85610-4-RR (same clone as 85610-4-PBS)

    WB analysis of human urine using 85610-4-RR (same clone as 85610-4-PBS)

    human urine sample were subjected to SDS PAGE followed by western blot with 85610-4-RR (PGLYRP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85610-4-PBS in a different storage buffer formulation.

  • IHC staining of mouse spleen using 85610-4-RR (same clone as 85610-4-PBS)

    IHC staining of mouse spleen using 85610-4-RR (same clone as 85610-4-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 85610-4-RR (PGLYRP1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85610-4-PBS in a different storage buffer formulation.

  • IF Staining of mouse spleen using 85610-4-RR (same clone as 85610-4-PBS)

    IF Staining of mouse spleen using 85610-4-RR (same clone as 85610-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse spleen tissue using PGLYRP1 antibody (85610-4-RR, Clone: 243004F5 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85610-4-PBS in a different storage buffer formulation.

  • IF Staining of mouse spleen using 85610-4-RR (same clone as 85610-4-PBS)

    IF Staining of mouse spleen using 85610-4-RR (same clone as 85610-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse spleen tissue using PGLYRP1 antibody (85610-4-RR, Clone: 243004F5 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85610-4-PBS in a different storage buffer formulation.

PGLYRP1 Recombinant monoclonal antibody, PBS Only

PGLYRP1 Uni-rAb® Recombinant Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 85610-4-PBS

产品说明书

CloneNo. 243004F5

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF-P, Indirect ELISA

别名

PGLYRP, PGRP, PGRP S, PGRPS, PGRP-S

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

85610-4-PBS targets PGLYRP1 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Eg3122

Product name: Recombinant Human PGLYRP1 protein (rFc Tag)

Source: mammalian cells-derived, V37

Tag: C-rFc

Domain: 22-196 aa of NM_005091.2

Sequence: QETEDPACCSPIVPRNEWKALASECAQHLSLPLRYVVVSHTAGSSCNTPASCQQQARNVQHYHMKTLGWCDVGYNFLIGEDGLVYEGRGWNFTGAHSGHLWNPMSIGISFMGNYMDRVPTPQAIRAAQGLLACGVAQGALRSNYVLKGHRDVQRTLSPGNQLYHLIQNWPHYRSP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 peptidoglycan recognition protein 1
别名 PGLYRP, PGRP, PGRP S, PGRPS, PGRP-S
计算分子量22 kDa
观测分子量25 kDa
GenBank蛋白编号NM_005091.2
基因名称 PGLYRP1
Gene ID (NCBI) 8993
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDO75594
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Peptidoglycan recognition protein 1 (PGLYRP1, also known as PGRP-S) belongs to a family of evolutionary conserved innate immunity proteins, which in mammals also include PGLYRP2, PGLYRP3, and PGLYRP4 (PMID: 17275309; 20418257). PGLYRP1 is highly expressed in polymorphonuclear leukocytes and to a lower extent in many non-immune cells (PMID: 20418257). It recognizes bacterial peptidoglycan and functions in antibacterial immunity and inflammation (PMID: 20418257). PGLYRP1 has been identified as a ligand for TREM-1 (PMID: 25595774).

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