验证数据展示
产品信息
85610-4-PBS targets PGLYRP1 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, IF-P, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | PGLYRP1 fusion protein Eg3122 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | peptidoglycan recognition protein 1 |
别名 | PGLYRP, PGRP, PGRP S, PGRPS, PGRP-S |
计算分子量 | 22 kDa |
观测分子量 | 25 kDa |
GenBank蛋白编号 | NM_005091.2 |
基因名称 | PGLYRP1 |
Gene ID (NCBI) | 8993 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | O75594 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Peptidoglycan recognition protein 1 (PGLYRP1, also known as PGRP-S) belongs to a family of evolutionary conserved innate immunity proteins, which in mammals also include PGLYRP2, PGLYRP3, and PGLYRP4 (PMID: 17275309; 20418257). PGLYRP1 is highly expressed in polymorphonuclear leukocytes and to a lower extent in many non-immune cells (PMID: 20418257). It recognizes bacterial peptidoglycan and functions in antibacterial immunity and inflammation (PMID: 20418257). PGLYRP1 has been identified as a ligand for TREM-1 (PMID: 25595774).