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验证数据展示

  • FC experiment of NIH/3T3 using 98256-1-RR (same clone as 98256-1-PBS)

    FC experiment of NIH/3T3 using 98256-1-RR (same clone as 98256-1-PBS)

    1x10^6 NIH/3T3 cells were surface stained with 0.25 ug Anti-Mouse PDGFR alpha/CD140a Rabbit Recombinant Antibody (98256-1-RR, Clone: 242025B3) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98256-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98256-1-RR

    Affinity and Kinetic Characterization of 98256-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98256-1-RR against Mouse PDGFR alpha/CD140a were performed. The affinity constant is below 1 pM.

Anti-Mouse PDGFR alpha/CD140a Rabbit Recombinant Antibody, PBS Only

PDGFR alpha/CD140a Uni-rAbTM Recombinant Antibody for FC
Cat No. 98256-1-PBS

产品说明书

CloneNo. 242025B3

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

EC:2.7.10.1, CD140a, CD140 antigen-like family member A, Alpha-type platelet-derived growth factor receptor, Alpha platelet-derived growth factor receptor

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98256-1-PBS targets PDGFR alpha/CD140a in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 platelet derived growth factor receptor, alpha polypeptide
别名 EC:2.7.10.1, CD140a, CD140 antigen-like family member A, Alpha-type platelet-derived growth factor receptor, Alpha platelet-derived growth factor receptor
计算分子量123kDa
GenBank蛋白编号NM_001083316.2
基因名称 Pdgfra
Gene ID (NCBI) 18595
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP26618-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Platelet-derived growth factor receptor alpha (PDGFR alpha, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival, and chemotaxis. Mutations in the PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.