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验证数据展示

  • WB analysis using 83503-1-RR (same clone as 83503-1-PBS)

    WB analysis using 83503-1-RR (same clone as 83503-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83503-1-RR (PDE6D antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83503-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 83503-1-RR (same clone as 83503-1-PBS)

    WB analysis of HeLa using 83503-1-RR (same clone as 83503-1-PBS)

    WB result of PDE6D antibody (83503-1-RR; 1:4000; incubated at room temperature for 1.5 hours) with sh-Control and sh-PDE6D transfected HeLa cells. This data was developed using the same antibody clone with 83503-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

PDE6D Recombinant antibody, PBS Only

PDE6D Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 83503-1-PBS

产品说明书

CloneNo. 230546H1

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA

别名

PDED, 230546H1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

83503-1-PBS targets PDE6D in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 PDE6D fusion protein Ag29563 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 phosphodiesterase 6D, cGMP-specific, rod, delta
别名 PDED, 230546H1
计算分子量 17 KDa
观测分子量 14-17 kDa
GenBank蛋白编号NM_002601
基因名称 PDE6D
Gene ID (NCBI) 5147
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDO43924
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PDE6D, also known as PDED, belongs to the PDE6D/unc-119 family. PDE6D is a ubiquitously expressed prenyl-binding protein. By binding to prenyl moieties, PDE6D mediates the shuttling of prenylated proteins between membranes. Thereby, it regulates the membrane association of Ras and Rap GTPases (PMID: 36672247). In addition, research has shown that PDE6D is overexpressed in liver cancer and correlated with tumor stages, grading, and ERK activation (PMID: 30901922). The calculated molecular weight of PDE6D is 17 kDa.