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Host
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Species Reactivity
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验证数据展示

  • WB analysis of Jurkat using 67565-1-Ig (same clone as 67565-1-PBS)

    WB analysis of Jurkat using 67565-1-Ig (same clone as 67565-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 67565-1-Ig (PDE6D antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67565-1-PBS in a different storage buffer formulation.

  • WB analysis using 67565-1-Ig (same clone as 67565-1-PBS)

    WB analysis using 67565-1-Ig (same clone as 67565-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67565-1-Ig (PDE6D antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67565-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 67565-1-Ig (same clone as 67565-1-PBS)

    IHC staining of mouse brain using 67565-1-Ig (same clone as 67565-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 67565-1-Ig (PDE6D antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67565-1-PBS in a different storage buffer formulation.

PDE6D Monoclonal antibody, PBS Only

PDE6D Monoclonal Antibody for WB, IHC, ELISA
Cat No. 67565-1-PBS

产品说明书

CloneNo. 1H4B6

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat, pig

应用

WB, IHC, ELISA

别名

PDED, 1H4B6

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67565-1-PBS targets PDE6D in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat, pig samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, mouse, rat, pig
免疫原 PDE6D fusion protein Ag29563 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 phosphodiesterase 6D, cGMP-specific, rod, delta
别名 PDED, 1H4B6
计算分子量 17 KDa
观测分子量 15-17 kDa
GenBank蛋白编号NM_002601
基因名称 PDE6D
Gene ID (NCBI) 5147
RRIDAB_2882779
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDO43924
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PDE6D, also known as PDED, belongs to the PDE6D/unc-119 family. PDE6D is a ubiquitously expressed prenyl-binding protein. By binding to prenyl moieties, PDE6D mediates the shuttling of prenylated proteins between membranes. Thereby, it regulates the membrane association of Ras and Rap GTPases (PMID: 36672247). In addition, research has shown that PDE6D is overexpressed in liver cancer and correlated with tumor stages, grading, and ERK activation (PMID: 30901922). The calculated molecular weight of PDE6D is 17 kDa.