验证数据展示
产品信息
23848-1-PBS targets PCDHGC5 in IHC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IHC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag20867 Product name: Recombinant human PCDHGC5 protein Source: e coli.-derived, PET30a Tag: 6*His Domain: 31-402 aa of BC112081 Sequence: LRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSEN 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | protocadherin gamma subfamily C, 5 |
| 别名 | Protocadherin gamma-C5, PCDHGC, PCDH-gamma-C5 |
| 计算分子量 | 581aa,65 kDa; 944aa,102 kDa |
| GenBank蛋白编号 | BC112081 |
| 基因名称 | PCDHGC5 |
| Gene ID (NCBI) | 56097 |
| RRID | AB_3669420 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen Affinity purified |
| UNIPROT ID | Q9Y5F6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). Disruption of the γ-protocadherins locus causes neonatal lethality, and Pcdhgc3, Pcdhgc4, and Pcdhgc5 are essential for the observed lethality.
