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验证数据展示

  • IHC staining of human lung cancer using 23848-1-AP

    IHC staining of human lung cancer using 23848-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 23848-1-AP (PCDHGC5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human lung cancer using 23848-1-AP

    IHC staining of human lung cancer using 23848-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 23848-1-AP (PCDHGC5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

PCDHGC5 Polyclonal antibody

PCDHGC5 Polyclonal Antibody for IHC, ELISA
Cat No. 23848-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, ELISA

别名

Protocadherin gamma-C5, PCDHGC, PCDH-gamma-C5

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive IHC detected inhuman lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

23848-1-AP targets PCDHGC5 in IHC, ELISA applications and shows reactivity with human samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human
免疫原 PCDHGC5 fusion protein Ag20867 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 protocadherin gamma subfamily C, 5
别名 Protocadherin gamma-C5, PCDHGC, PCDH-gamma-C5
计算分子量581aa,65 kDa; 944aa,102 kDa
GenBank蛋白编号BC112081
基因名称 PCDHGC5
Gene ID (NCBI) 56097
RRIDAB_3669420
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen Affinity purified
UNIPROT IDQ9Y5F6
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). Disruption of the γ-protocadherins locus causes neonatal lethality, and Pcdhgc3, Pcdhgc4, and Pcdhgc5 are essential for the observed lethality.

实验方案

Product Specific Protocols
IHC protocol for PCDHGC5 antibody 23848-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols