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验证数据展示

  • IHC staining of mouse brain using 10857-1-AP (same clone as 10857-1-PBS)

    IHC staining of mouse brain using 10857-1-AP (same clone as 10857-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 10857-1-AP (PCDHGC3 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10857-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 10857-1-AP (same clone as 10857-1-PBS)

    IHC staining of mouse brain using 10857-1-AP (same clone as 10857-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 10857-1-AP (PCDHGC3 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10857-1-PBS in a different storage buffer formulation.

  • IF Staining of SH-SY5Y using 10857-1-AP (same clone as 10857-1-PBS)

    IF Staining of SH-SY5Y using 10857-1-AP (same clone as 10857-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using PCDHGC3 antibody (10857-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 10857-1-PBS in a different storage buffer formulation.

PCDHGC3 Polyclonal antibody, PBS Only

PCDHGC3 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 10857-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, IF/ICC, Indirect ELISA

别名

PC-43, PCDH2, PCDH-gamma-C3, Protocadherin gamma-C3, Protocadherin-2

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

10857-1-PBS targets PCDHGC3 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag1243

Product name: Recombinant human PCDHGC3 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 612-934 aa of BC019299

Sequence: GSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 protocadherin gamma subfamily C, 3
别名 PC-43, PCDH2, PCDH-gamma-C3, Protocadherin gamma-C3, Protocadherin-2
计算分子量 150 kDa
GenBank蛋白编号BC019299
基因名称 PCDHGC3
Gene ID (NCBI) 5098
RRIDAB_2159713
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UN70
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PCDHGC3, a member of the PCDHγ cluster, has been described in some studies as a tumor suppressor that promotes the apoptosis of tumor cells, as well as suppresses the Wnt- and mTOR-signaling pathways, which negatively affects the growth of various tumors such as Wilms tumors, breast cancer, or prostate cancer.

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