验证数据展示
产品信息
24966-1-PBS targets PAQR7 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag21655 Product name: Recombinant human PAQR7 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-69 aa of BC034015 Sequence: MAMAQKLSHLLPSLRQVIQEPQLSLQPEPVFTVDRAEVPPLFWKPYIYAGYRPLHQTWRFYFRTLFQQH 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | progestin and adipoQ receptor family member VII |
| 别名 | mSR, MRPA, MPRA, mPR alpha, Membrane progesterone receptor alpha |
| 计算分子量 | 346 aa, 40 kDa |
| 观测分子量 | 40 kDa |
| GenBank蛋白编号 | BC034015 |
| 基因名称 | PAQR7 |
| Gene ID (NCBI) | 164091 |
| RRID | AB_3742132 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q86WK9 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Progestin and adipoQ receptor 7 (PAQR7), also called membrane P4 receptor α (mPRα), is a membrane protein with seven transmembrane domains, similar to G protein-coupled receptors (PMID: 34217103). Studies have shown that PAQR7 has important physiological functions in various reproductive tissues (PMID: 12601167). In addition, PAQR7 participates in the antimitotic action of P4 in human GCs and luteal cells, and P4's ability to suppress entry into the cell cycle was dependent on PAQR7 but not nuclear progesterone receptor (PGR) (PMID: 26203174).
