验证数据展示
经过测试的应用
| Positive WB detected in | HEK-293 cells, HeLa cells, SW480 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
24966-1-AP targets PAQR7 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | PAQR7 fusion protein Ag21655 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | progestin and adipoQ receptor family member VII |
| 别名 | mSR, MRPA, MPRA, mPR alpha, Membrane progesterone receptor alpha |
| 计算分子量 | 346 aa, 40 kDa |
| 观测分子量 | 40 kDa |
| GenBank蛋白编号 | BC034015 |
| 基因名称 | PAQR7 |
| Gene ID (NCBI) | 164091 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q86WK9 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Progestin and adipoQ receptor 7 (PAQR7), also called membrane P4 receptor α (mPRα), is a membrane protein with seven transmembrane domains, similar to G protein-coupled receptors (PMID: 34217103). Studies have shown that PAQR7 has important physiological functions in various reproductive tissues (PMID: 12601167). In addition, PAQR7 participates in the antimitotic action of P4 in human GCs and luteal cells, and P4's ability to suppress entry into the cell cycle was dependent on PAQR7 but not nuclear progesterone receptor (PGR) (PMID: 26203174).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for PAQR7 antibody 24966-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |