验证数据展示
产品信息
98696-1-PBS targets PANX2 in IHC, FC applications and shows reactivity with human samples.
| 经测试应用 | IHC, FC Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | pannexin 2 |
| 别名 | hPANX2, pannexin 2, PX2 |
| 计算分子量 | 677 aa, 74 kDa |
| GenBank蛋白编号 | BC101023 |
| 基因名称 | PANX2 |
| Gene ID (NCBI) | 56666 |
| RRID | AB_3746281 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q96RD6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Pannexins are glycoproteins that form functional single-membrane channels, which mediate ATP release in response to a variety of physiological and pathological stimuli (PMID: 33913372). The pannexin family consists of three members, namely PANX1, PANX2, and PANX3 (PMID: 22305965). PANX2 was initially predicted to be expressed selectively in the central nervous system, but was later shown to have broad expression across multiple tissues, including skin, skeletal muscle, eye, and colon (PMID: 15028292; 25505382; 25773474). PANX2 is involved in pathophysiological processes of neurological and cancer diseases (PMID: 19749789; 33913372; 39389335).
