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验证数据展示

  • WB analysis using 68873-5-Ig (same clone as 68873-5-PBS)

    WB analysis using 68873-5-Ig (same clone as 68873-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68873-5-Ig (PANX1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68873-5-PBS in a different storage buffer formulation.

  • WB analysis of Neuro-2a using 68873-5-Ig (same clone as 68873-5-PBS)

    WB analysis of Neuro-2a using 68873-5-Ig (same clone as 68873-5-PBS)

    Neuro-2a cells were subjected to SDS PAGE followed by western blot with 68873-5-Ig (PANX1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68873-5-PBS in a different storage buffer formulation.

PANX1 Monoclonal antibody, PBS Only

PANX1 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68873-5-PBS

产品说明书

CloneNo. 3G4B10

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

Caspase-activated pannexin-1, Innexin, MRS1, OOMD7, OZEMA7

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

68873-5-PBS targets PANX1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag33689

Product name: Recombinant human PANX1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 126-426 aa of BC016931

Sequence: FWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENLGQSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNARQRLLDSSC

种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 pannexin 1
别名 Caspase-activated pannexin-1, Innexin, MRS1, OOMD7, OZEMA7
计算分子量 426 aa, 48 kDa
观测分子量 45-50 kDa
GenBank蛋白编号BC016931
基因名称 PANX1
Gene ID (NCBI) 24145
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ96RD7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PANX1, also named as MRS1, belongs to the pannexin family. It plays a role as a Ca2+-leak channel to regulate ER Ca2+ homeostasis. It is a structural component of the gap junctions and the hemichannels. PANX1 induced the formation of intercellular channels with characteristics of gap junctions. PANX1 is 48-kDa protein which contains 4 transmembrane domains and cytoplasmic N and C termini. It is a mediator of find-me signal/nucleotide release from apoptotic cells.

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