验证数据展示
产品信息
60167-1-Ig targets Palladin-Specific in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Mouse / IgM |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | palladin, cytoskeletal associated protein |
| 别名 | |
| 计算分子量 | 151 kDa |
| 观测分子量 | 80 kDa, 120 kDa, 160 kDa |
| GenBank蛋白编号 | NM_016081 |
| 基因名称 | palladin |
| Gene ID (NCBI) | 23022 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Caprylic acid/ammonium sulfate precipitation |
| UNIPROT ID | Q8WX93 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Paladin belongs to the myotilin/palladin family. Palladin is a widely expressed protein found in stress fibers, focal adhesions, growth cones, Z-discs, and other actin-based subcellular structures. It is a cytoskeletal protein required for organization of normal actin cytoskeleton. It functions in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. Palladin has multiple transcription isoforms, specialized for different functions. This antibody, generated against N-terminal peptide of palladin, recognizes 200 kD, 140 kD, and 65 kD isoforms of this protein.