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验证数据展示

  • FC experiment of BALB/c mouse splenocytes using 98381-1-RR (same clone as 98381-1-PBS)

    FC experiment of BALB/c mouse splenocytes using 98381-1-RR (same clone as 98381-1-PBS)

    1x10^6 untreated or Anti-IgM and CD40 treated BALB/c mouse splenocytes were surface stained with 0.25 ug Anti-Mouse OX40 Ligand/TNFSF4 Rabbit RecAb (98381-1-RR, Clone:242227B1) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 488 Anti-Mouse CD19 (1D3) (CL488-65290, Clone: 1D3). Cells were not fixed. This data was developed using the same antibody clone with 98381-1-PBS in a different storage buffer formulation.

  • FC experiment of BALB/c mouse splenocytes using 98381-1-RR (same clone as 98381-1-PBS)

    FC experiment of BALB/c mouse splenocytes using 98381-1-RR (same clone as 98381-1-PBS)

    1x10^6 Anti-IgM and CD40 treated BALB/c mouse splenocytes were surface stained with 0.25 ug Anti-Mouse OX40 Ligand/TNFSF4 Rabbit RecAb (98381-1-RR, Clone:242227B1) (red) and PE-Conjugated Goat Anti-Rabbit IgG(H+L), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). 1x10^6 untreated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse OX40 Ligand/TNFSF4 Rabbit RecAb (98381-1-RR, Clone:242227B1) (black, dashed) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98381-1-PBS in a different storage buffer formulation.

Anti-Mouse OX40L/TNFSF4 Rabbit Recombinant Antibody, PBS Only

OX40L/TNFSF4 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98381-1-PBS

产品说明书

CloneNo. 242227B1

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

CD252, OX40 ligand, OX40L, Tnfsf4, Tumor necrosis factor ligand superfamily member 4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98381-1-PBS targets OX40L/TNFSF4 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 OX40L/TNFSF4 fusion protein Eg1573 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tumor necrosis factor (ligand) superfamily, member 4
别名 CD252, OX40 ligand, OX40L, Tnfsf4, Tumor necrosis factor ligand superfamily member 4
计算分子量22kDa
GenBank蛋白编号NM_009452.2
基因名称 Tnfsf4
Gene ID (NCBI) 22164
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP43488
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The tumour necrosis factor ligand superfamily member 4 gene (TNFSF4, OX40L), which encodes for the T cell costimulatory molecule OX40 ligand, has been identified as a susceptibility gene for the development of systemic lupus erythematosus (SLE). OX40L/TNFSF4/CD252 is a co-stimulatory checkpoint protein expressed by several types of immune and non-immune cells (PMID: 15750594, 19778912). TNFSF4 mRNA is expressed in melanoma cell lines and melanoma samples, including those with low lymphocytic infiltrates, and is not associated with the ulceration status of the primary tumor (PMID: 31501955).