验证数据展示
产品信息
33794-1-PBS targets OTOG in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Eg5591 Product name: Recombinant human OTOG protein Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 1634-1796 aa of NM_001277269.2 Sequence: VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAA 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | otogelin |
| 别名 | OTGN, Otogelin |
| 计算分子量 | 315 kDa |
| 观测分子量 | 314 kDa |
| GenBank蛋白编号 | NM_001277269.2 |
| 基因名称 | OTOG |
| Gene ID (NCBI) | 340990 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q6ZRI0-1 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
OTOG (Otogelin) is a glycoprotein that is highly expressed in the inner ear and is essential for maintaining hearing and balance functions. It belongs to the mucin-like glycoprotein family and is a large extracellular matrix protein with numerous glycosylation sites. This allows it to form gel-like structures that provide structural support during mechanical transduction in the inner ear. Mutations or loss of function in the OTOG gene can lead to severe hereditary deafness and vestibular dysfunction. There are two isoforms of OTOG, with molecular weights of 160 kDa and 314 kDa respectively.
