OSBPL5, also known as oxysterol binding protein like 5, is a protein-coding gene in humans. It is a member of the oxysterol-binding protein (OSBP) family, which consists of intracellular lipid receptors that play a crucial role in maintaining cholesterol balance in the body. It is expressed ubiquitously in various tissues, including the spleen and endometrium. OSBPL5 is classified as a plasma protein and transporter, with a predicted subcellular location in the membrane and intracellular compartments. The protein has been implicated in several biological processes and is involved in the transport of lipids and other molecules between organelles. In terms of disease association, OSBPL5 has been linked to conditions such as Lenz-Majewski hyperostotic dwarfism. Additionally, the OSBPL family of proteins, including OSBPL5, has been suggested to play a role in cancer development, although specific roles in different types of cancer are still being investigated (PMID: 36918840). The molecular weight of OSBPL5 is 98 kDa.