验证数据展示
经过测试的应用
| Positive WB detected in | mouse liver tissue, rat liver tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:12000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
27870-1-AP targets OSBPL5 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | OSBPL5 fusion protein Ag27304 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | oxysterol binding protein-like 5 |
| 别名 | OSBP related protein 5, ORP-5, ORP5, ORP 5, OBPH1 |
| 计算分子量 | 811 aa, 91 kDa |
| 观测分子量 | 100 kDa |
| GenBank蛋白编号 | BC032646 |
| 基因名称 | OSBPL5 |
| Gene ID (NCBI) | 114879 |
| RRID | AB_3669627 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9H0X9 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
OSBPL5, also known as oxysterol binding protein like 5, is a protein-coding gene in humans. It is a member of the oxysterol-binding protein (OSBP) family, which consists of intracellular lipid receptors that play a crucial role in maintaining cholesterol balance in the body. It is expressed ubiquitously in various tissues, including the spleen and endometrium. OSBPL5 is classified as a plasma protein and transporter, with a predicted subcellular location in the membrane and intracellular compartments. The protein has been implicated in several biological processes and is involved in the transport of lipids and other molecules between organelles. In terms of disease association, OSBPL5 has been linked to conditions such as Lenz-Majewski hyperostotic dwarfism. Additionally, the OSBPL family of proteins, including OSBPL5, has been suggested to play a role in cancer development, although specific roles in different types of cancer are still being investigated (PMID: 36918840). The molecular weight of OSBPL5 is 98 kDa.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for OSBPL5 antibody 27870-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |