CoraLite® Plus 488-conjugated ORM2-Specific Monoclonal antibody
ORM2-Specific Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
4E9H10
验证数据展示
经过测试的应用
| Positive IF detected in | HepG2 cells |
For other applications, we recommend the unconjugated version of this antibody, 66217-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-66217 targets ORM2-Specific in IF applications and shows reactivity with human samples.
| Tested Applications | IF/ICC |
| Tested Reactivity | human |
| Immunogen | ORM2-Specific fusion protein Ag18984 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | orosomucoid 2 |
| Synonyms | AGP 2, AGP B, AGP B', AGP2, Alpha 1 acid glycoprotein 2, OMD 2, ORM2, orosomucoid 2 |
| Calculated Molecular Weight | 24 kDa |
| Observed Molecular Weight | 45 kDa |
| GenBank Accession Number | BC015964 |
| Gene Symbol | ORM2 |
| Gene ID (NCBI) | 5005 |
| RRID | AB_2919302 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P19652 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ORM2, also named as AGP2 and OMD 2, belongs to the calycin superfamily and Lipocalin family. It functions as transport protein in the blood stream. ORM2 binds various hydrophobic ligands in the interior of its beta-barrel domain. It also binds synthetic drugs and influences their distribution and availability. ORM2 appears to function in modulating the activity of the immune system during the acute-phase reaction. ORM2 is one of the conserved endoplasmic reticulum membrane proteins which regulating lipid homeostasis and protein quality control. This antibody can specially recognize ORM2. It recognizes a band about 45 kDa in human plasma which may be due to the glycosylation of ORM2 or the dimer formation of the protein.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 ORM2-Specific antibody CL488-66217 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |