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OPCML Polyclonal antibody

OPCML Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 17962-1-AP

Print datasheet

Synonyms

IgLON family member 1, IGLON1, OBCAM, OPCM, OPCML

验证数据展示

  • WB analysis using 17962-1-AP

    WB analysis using 17962-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 17962-1-AP (OPCML antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse pancreas tissue, rat pancreas tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

17962-1-AP targets OPCML in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA
Tested Reactivity human, mouse, rat
Immunogen OPCML fusion protein Ag12560 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name opioid binding protein/cell adhesion molecule-like
Synonyms IgLON family member 1, IGLON1, OBCAM, OPCM, OPCML
Calculated Molecular Weight 345 aa, 38 kDa
Observed Molecular Weight45 kDa
GenBank Accession NumberBC074773
Gene Symbol OPCML
Gene ID (NCBI) 4978
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ14982
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

OPCML, also called opioid-binding cell adhesion molecule (OBCAM), belongs to the IgLON limbic system-associated membrane protein (LSAMP, OPCML/OBCAM, neurotrimin) family of IgG domain containing glycosylphosphatidylinositol-anchored cell adhesion molecules. Originally isolated from brain, OPCMLis also expressed in stomach, ovary, heart, placenta, testis, kidney, liver, pancreas and colon. OPCML has been identified as a tumour suppressor, which inhibited tumor growth in some cancers including ovarian cancer, lung cancer and prostate cancer (PMID: 19176311; 28407749).

实验方案

Product Specific Protocols
WB protocol for OPCML antibody 17962-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols