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验证数据展示

  • IHC staining of human brain using 22851-1-AP (same clone as 22851-1-PBS)

    IHC staining of human brain using 22851-1-AP (same clone as 22851-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain slide using 22851-1-AP (OFD1 Antibody) at dilution of 1:50. (under 10x lens). This data was developed using the same antibody clone with 22851-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 22851-1-AP (same clone as 22851-1-PBS)

    IHC staining of human brain using 22851-1-AP (same clone as 22851-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain slide using 22851-1-AP (OFD1 Antibody) at dilution of 1:50. (under 40x lens). This data was developed using the same antibody clone with 22851-1-PBS in a different storage buffer formulation.

  • IF Staining of HEK-293 using 22851-1-AP (same clone as 22851-1-PBS)

    IF Staining of HEK-293 using 22851-1-AP (same clone as 22851-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HEK-293 cells using OFD1 antibody (22851-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 22851-1-PBS in a different storage buffer formulation.

  • IF Staining of hTERT-RPE1 using 22851-1-AP (same clone as 22851-1-PBS)

    IF Staining of hTERT-RPE1 using 22851-1-AP (same clone as 22851-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed hTERT-RPE1 cells using OFD1 antibody (22851-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CoraLite®594 ARL13B antibody (CL594-17711, red). This data was developed using the same antibody clone with 22851-1-PBS in a different storage buffer formulation.

OFD1 Polyclonal antibody, PBS Only

OFD1 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 22851-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, IF/ICC, Indirect ELISA

别名

71 7A, Centriole and centriolar satellite protein OFD1, CXorf5, Oral-facial-digital syndrome 1 protein, Protein 71 7A

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

22851-1-PBS targets OFD1 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag18898

Product name: Recombinant human OFD1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-305 aa of BC096344

Sequence: MMAQSNMFTVADVLSQDELRKKLYQTFKDRGILDTLKTQLRNQLIHELMHPVLSGELQPRSISVEGSSLLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKVFTMQDLLQLIKINPTSSLYKSLVSGSDKENQKGFLMHFLKELAEYHQAKESCNMETQTSSTFNRDSLAEKLQLIDDQFADAYPQRIKFESLEIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQ

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 oral-facial-digital syndrome 1
别名 71 7A, Centriole and centriolar satellite protein OFD1, CXorf5, Oral-facial-digital syndrome 1 protein, Protein 71 7A
计算分子量 1012 aa, 117 kDa
观测分子量 110-120 kDa
GenBank蛋白编号BC096344
基因名称 OFD1
Gene ID (NCBI) 8481
RRIDAB_2879177
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO75665
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

OFD1, also named CXorf5 and 71-7A, belongs to the OFD1 family. It has been implicated in several developmental syndromes, including a male-lethal X-linked dominant condition, Oral-Facial-Digital type 1 (OFD1) syndrome, X-linked recessiveSimpson-Golabi-Behmel syndrome type 2 (SGBS2), and Joubert syndrome and related disorders (JSRDs). It is a component of the centrioles controlling mother and daughter centrioles' length. It recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. OFD1 plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. This antibody recognizes all the isoforms of OFD1. The 43 kDa is isoform 2. The ~80 kDa band is unknown.

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