验证数据展示
产品信息
34385-1-PBS targets NUDT7 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IP, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag41199 Product name: Recombinant human NUDT7 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 37-172 aa of NM_001105663 Sequence: YNKYSVLLPLVAKEGKLHLLFTVRSEKLRRAPGEVCFPGGKRDPTDMDDAATALREAQEEVGLRPHQVEVVCCLVPCLIDTDTLITPFVGLIDHNFQAQPNPAEVKDVFLVPLAYFLHPQVHDQHYVTRLGHRFIN 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| 别名 | Nucleoside diphosphate-linked moiety X motif 7, Nucleoside diphosphate-linked moiety X motif 7 (Nudix motif 7), Peroxisomal coenzyme A diphosphatase NUDT7 |
| 计算分子量 | 238aa, 27 kDa |
| 观测分子量 | 30 kDa |
| GenBank蛋白编号 | NM_001105663 |
| 基因名称 | NUDT7 |
| Gene ID (NCBI) | 283927 |
| RRID | AB_3743196 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | P0C024 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Peroxisomal coenzyme A diphosphatase NUDT7, a peroxisomal Nudix hydrolase, mainly localizes to the peroxisomal matrix and catalyzes hydrolysis of CoA/acyl-CoAs, regulating lipid metabolism and CoA homeostasis (PMID: 11415433; 25110012). Its dysregulation links to diabetes, Kras-driven colorectal cancer, neurodegeneration with brain iron accumulation, and osteoarthritis (PMID: 32131398; 24847269; 30143643).

