Neuropilin 1 Polyclonal antibody
Neuropilin 1 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
ELISA
Conjugate
Unconjugated
验证数据展示
产品信息
10612-1-AP targets Neuropilin 1 in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA |
| Tested Reactivity | human, mouse, rat |
| Immunogen | Neuropilin 1 fusion protein Ag0931 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | neuropilin 1 |
| Synonyms | BDCA4, CD304, neuropilin 1, NRP, NRP1, VEGF165R |
| Calculated Molecular Weight | 103 kDa |
| GenBank Accession Number | BC007737 |
| Gene Symbol | NRP1 |
| Gene ID (NCBI) | 8829 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O14786 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Neuropilin-1 (NRP1) is a transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.