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NR1H2 Monoclonal antibody, PBS Only

NR1H2 Monoclonal Antibody for WB, ELISA
Cat No. 60345-1-PBS

产品说明书

CloneNo. 1E12B10

宿主/亚型

Mouse / IgG1

种属反应性

human, pig

应用

WB, ELISA

1E12B10, Liver X receptor beta, LXR b, LXRB, NER

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存


产品信息

60345-1-PBS targets NR1H2 in WB, ELISA applications and shows reactivity with human, pig samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, pig
免疫原 NR1H2 fusion protein Ag5635 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 nuclear receptor subfamily 1, group H, member 2
别名 1E12B10, Liver X receptor beta, LXR b, LXRB, NER
计算分子量 51 kDa
观测分子量 51 kDa
GenBank蛋白编号BC047750
基因名称 NR1H2
Gene ID (NCBI) 7376
RRIDAB_2881454
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP55055
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NR1H2, also known as LXRB, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. It preferentially bind to double-stranded oligonucleotide direct repeats, which have the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). It involves in the regulation of cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.

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