NPTX2 Recombinant antibody

NPTX2 Uni-rAbTM Recombinant Antibody for WB, IHC, ELISA
Cat No. 86203-1-RR

产品说明书

CloneNo. 250809A7

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA

Neuronal pentraxin II, Neuronal pentraxin-2, NP2, NP-II

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存


经过测试的应用

Positive WB detected inmouse brain tissue, SH-SY5Y cells, rat brain tissue
Positive IHC detected inhuman pancreas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:5000-1:50000
Immunohistochemistry (IHC)IHC : 1:250-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

86203-1-RR targets NPTX2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 NPTX2 fusion protein Ag33808 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 neuronal pentraxin II
别名 Neuronal pentraxin II, Neuronal pentraxin-2, NP2, NP-II
计算分子量 47 kDa
观测分子量 47-50 kDa
GenBank蛋白编号BC009924
基因名称 NPTX2
Gene ID (NCBI) 4885
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP47972
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Neuronal pentraxins constitute a family of proteins that are homologous to C-reactive protein (CRP) and serum amyloid P component (SAP), including NPTX1, NPTX2, and the neuronal pentraxin receptor (NPTXR). NPTX2, also known as NARP (neuronal activity-regulated pentaxin), is a secreted protein involved in excitatory synapse formation. It also plays a role in the clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. NPTX2 is highly up-regulated in Parkinson's disease (PD), suggesting it may be involved in the pathology of PD. (PMID: 12895424; 17987278; 10748068)

实验方案

Product Specific Protocols
WB protocol for NPTX2 antibody 86203-1-RRDownload protocol
IHC protocol for NPTX2 antibody 86203-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
Loading...