验证数据展示
产品信息
87818-1-PBS targets NKG2E in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Eg4703 Product name: recombinant human NKG2E protein Source: mammalian cells-derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 94-240 aa of NM_002261.3 Sequence: IPFLEQNNSSPNARTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLQACASKNSSSLLCIDNEEEMKFLASILPSSWIGVFRNSSHHPWVTINGLAFKHEIKDSDHAERNCAMLHVRGLISDQCGSSRIIRRGFIMLTRLVLNS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | killer cell lectin-like receptor subfamily C, member 3 |
| 别名 | KLRC3, NK cell receptor E, NKG2 E, NKG2 E activating NK receptor |
| 计算分子量 | 37 kDa |
| 观测分子量 | 45-60 kDa |
| GenBank蛋白编号 | NM_002261.3 |
| 基因名称 | KLRC3 |
| Gene ID (NCBI) | 3823 |
| RRID | AB_3745768 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q07444-1 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NKG2E, also known as killer cell lectin-like receptor subfamily C member 3 (KLRC3), is a transmembrane protein primarily expressed on the surface of natural killer (NK) cells and some cytotoxic T-cells. As a member of the NKG2 family, it functions as a receptor for the recognition of non-classical MHC class I molecule HLA-E, playing a role in immune surveillance. Structurally, NKG2E is a type II membrane protein containing a C-type lectin domain in its extracellular region. The immunogenic sequence of NKG2E shares 88% homology with that of NKG2A, leading to cross-reactivity.
