验证数据展示
产品信息
15672-1-PBS targets NFKBID in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag8139 Product name: Recombinant human NFKBID protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-150 aa of BC006273 Sequence: MRSCCVVQAGLQLLASSDPPSSASQSARITGVNHRTPPREIKSNKTVLHLAVQAANPTLVQLLLELPRGDLRTFVNMKAHGNTALHMAAALPPGPAQEAIVRHLLAAGADPTLRNLENEQPVHLLRPGPGPEGLRQLLKRSRVAPPGLSS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta |
| 别名 | I kappa B delta, I-kappa-B-delta, IkappaBNS, IkB delta, IkB-delta |
| 计算分子量 | 150 aa, 16 kDa |
| 观测分子量 | 33 kDa |
| GenBank蛋白编号 | BC006273 |
| 基因名称 | NFKBID |
| Gene ID (NCBI) | 84807 |
| RRID | AB_3741869 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8NI38 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NFKBID, also known as IkBNS, belongs to the IKB protein family of NFKB inhibitors and is induced by T-cell receptor stimulation(PMID: 11931770). NFKBID regulates the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. NFKBID plays a role in regulating inflammatory responses. NFKBID is involved in the induction of T helper 17 cells (Th17) differentiation upon antigen recognition by T cell antigen receptor (TCR). (PMID: 25347393)
