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验证数据展示

  • WB analysis of mouse skeletal muscle using 83934-1-RR (same clone as 83934-1-PBS)

    WB analysis of mouse skeletal muscle using 83934-1-RR (same clone as 83934-1-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 83934-1-RR (NEU2 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83934-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse skeletal muscle using 83934-1-RR (same clone as 83934-1-PBS)

    IHC staining of mouse skeletal muscle using 83934-1-RR (same clone as 83934-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 83934-1-RR (NEU2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83934-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse skeletal muscle using 83934-1-RR (same clone as 83934-1-PBS)

    IHC staining of mouse skeletal muscle using 83934-1-RR (same clone as 83934-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 83934-1-RR (NEU2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83934-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83934-1-RR

    Affinity and Kinetic Characterization of 83934-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83934-1-RR against Human NEU2 were performed. The affinity constant is 2.76 nM.

NEU2 Recombinant antibody, PBS Only

NEU2 Uni-rAbTM Recombinant Antibody for WB, IHC, ELISA
Cat No. 83934-1-PBS

产品说明书

CloneNo. 240685B3

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, ELISA

别名

240685B3, Cytosolic sialidase, EC:3.2.1.18, N acetyl alpha neuraminidase 2, N-acetyl-alpha-neuraminidase 2

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

83934-1-PBS targets NEU2 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, mouse
免疫原 NEU2 fusion protein Ag17386 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 sialidase 2 (cytosolic sialidase)
别名 240685B3, Cytosolic sialidase, EC:3.2.1.18, N acetyl alpha neuraminidase 2, N-acetyl-alpha-neuraminidase 2
计算分子量 380 aa, 42 kDa
观测分子量 42 kDa
GenBank蛋白编号BC107053
基因名称 NEU2
Gene ID (NCBI) 4759
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ9Y3R4
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NEU2, also named as Sialidase 2, neuraminidase 2, catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosaccharides. NEU2 is localized in the cytosol and plasma membrane and takes part in myoblast and neuronal differentiation. It is almost undetectable under normal physiological conditions, and was found to be involved into apoptotic events in pancreatic ductal adenocarcinoma, one of the most dangerous cancers due to poor diagnosis and prognosis. (PMID: 30439363)