验证数据展示
产品信息
29936-1-PBS targets NETO1 in IHC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IHC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag32177 Product name: Recombinant human NETO1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 23-213 aa of NM_138999 Sequence: TKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSK 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | neuropilin (NRP) and tolloid (TLL)-like 1 |
| 别名 | BTCL1, NETO 1 |
| 计算分子量 | 60 kDa |
| GenBank蛋白编号 | NM_138999 |
| 基因名称 | NETO1 |
| Gene ID (NCBI) | 81832 |
| RRID | AB_3742322 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8TDF5 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The NETO1 protein (neuropilin and tolloid-like protein 1) is a member of the NETO family. It is a type I transmembrane protein primarily expressed in the central nervous system. Serving as an important auxiliary subunit of glutamate receptors (especially kainate receptors and NMDA receptors), NETO1 plays a critical role in synaptic plasticity, learning, and memory by regulating receptor trafficking, gating properties, and synaptic localization. Its abnormalities are associated with neuropsychiatric disorders such as schizophrenia and epilepsy.
