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NBQX

NBQX (FG9202) 是强效、选择性和竞争性 AMPA 受体拮抗剂，具有神经保护和抗惊厥活性。

CAS号

118876-58-7

分子式

C12H8N4O6S

主要靶点

iGluR|GluR

仅限科研使用

Cat No : CM02673

Print datasheet

Synonyms

ischaemia|FG 9202|FG9202|FG-9202|iGluR|NBQX disodium salt|NBQX disodium salt|NBQX disodium|NBQX|AMPA|AMP|二羟基喹酮

验证数据展示

  • CAS No.: 118876-58-7

    NBQX
    CAS#: 118876-58-7

产品信息

NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.

CAS号 118876-58-7
分子式 C12H8N4O6S
主要靶点 iGluR|GluR
主要通路 神经科学|神经科学|离子通道
分子量 336.28
纯度 99.93%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
别名 ischaemia|FG 9202|FG9202|FG-9202|iGluR|NBQX disodium salt|NBQX disodium salt|NBQX disodium|NBQX|AMPA|AMP|二羟基喹酮

溶解度

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.95 mM);10% DMSO+90% Saline:3.33 mg/mL (9.9 mM);DMSO:125 mg/mL (371.71 mM)

参考文献

1.Gill et al (1992) The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline (NBQX) in a rat focal ischaemia model. Brain Res. 580 35
2.Namba et al (1994) Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy. Brain Res. 638 36
3.Sheardown et al (1993) The pharmacology of AMPA receptors and their antagonists. Stroke 24 146
4.Zeman and Lodge (1992) Pharmacological characterization of non-NMDA subtypes of glutamate receptors in the neonatal rat hemisected spinal cord in vitro. Br.J.Pharmacol. 106 367

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2
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