验证数据展示
产品信息
18829-1-AP targets NB-3 in ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | contactin 6 |
| 别名 | CNTN6, contactin 6, hNB 3, NB 3, NB3 |
| 计算分子量 | 1028 aa, 114 kDa |
| GenBank蛋白编号 | BC113118 |
| 基因名称 | NB-3 |
| Gene ID (NCBI) | 27255 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9UQ52 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CNTN6, also named as hNB-3, belongs to the immunoglobulin superfamily and Contactin family. CNTN6 contactins mediate cell surface interactions during nervous system development. CNTN6 participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. It involved in motor coordination