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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 82963-1-RR (same clone as 82963-1-PBS)

    WB analysis using 82963-1-RR (same clone as 82963-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82963-1-RR (NAGS antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82963-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82963-1-RR

    Affinity and Kinetic Characterization of 82963-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82963-1-RR against Human NAGS were performed. The affinity constant is below 1 pM.

NAGS Recombinant antibody, PBS Only

NAGS Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 82963-1-PBS

产品说明书

CloneNo. 230279D3

宿主/亚型

Rabbit / IgG

种属反应性

Human, mouse, rat

应用

WB, Indirect ELISA

别名

N-acetylglutamate synthase conserved domain form, EC:2.3.1.1, ARGA, Amino-acid acetyltransferase, AGAS

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

82963-1-PBS targets NAGS in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, mouse, rat
免疫原 NAGS fusion protein Ag16073 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 N-acetylglutamate synthase
别名 N-acetylglutamate synthase conserved domain form, EC:2.3.1.1, ARGA, Amino-acid acetyltransferase, AGAS
计算分子量 534 aa, 58 kDa
观测分子量 58 kDa
GenBank蛋白编号BC111713
基因名称 NAGS
Gene ID (NCBI) 162417
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ8N159
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

N-acetylglutamate synthase, also known as NAGS, is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAGS is the key enzyme for regulating the hepatic urea cycle and is also highly expressed in the kidney and gut. Deficiency of NAGS leads to hyperammonemia due to decreased activity of CPSI deprived of its cofactor NAG(PMID:12459178,12754705).