Mlkl Polyclonal antibody
Mlkl Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Mouse and More (1)
Applications
WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | 4T1 cells, NIH/3T3 cells |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 1 publications below |
产品信息
30145-1-AP targets Mlkl in WB, ELISA applications and shows reactivity with Mouse samples.
| Tested Applications | WB, ELISA |
| Cited Applications | WB |
| Tested Reactivity | Mouse |
| Cited Reactivity | mouse |
| Immunogen | Mlkl fusion protein Ag32514 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | mixed lineage kinase domain-like |
| Synonyms | 9130019I15Rik, Mlkl |
| Calculated Molecular Weight | 54kd |
| Observed Molecular Weight | 54 kDa |
| GenBank Accession Number | NM_001310613 |
| Gene Symbol | Mlkl |
| Gene ID (NCBI) | 74568 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9D2Y4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Mixed lineage kinase domain-like pseudokinase (Mlkl) belongs to the protein kinase superfamily and has two MW of 54 and 30 kDa. Mlkl plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in the necroptosis pathway. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for Mlkl antibody 30145-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|