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Methyl methanesulfonate

Methyl methanesulfonate 是一种DNA 烷基化剂,可以分别修饰腺嘌呤(为3-甲基腺嘌呤)和鸟嘌呤(7-甲基腺嘌呤),进而导致碱基错配和复制障碍。

CAS号

66-27-3

分子式

C2H6O3S

主要靶点

Necroptosis|DNA Alkylator/Crosslinker|DNA Alkylation|ROS|MDM-2/p53

仅限科研使用

Cat No : CM06927

Print datasheet

Synonyms

DNAAlkylation|DNA alkylator|DNA Alkylation|Methyl methanesulfonate|甲磺酸甲酯



产品信息

Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.

CAS号 66-27-3
分子式 C2H6O3S
主要靶点 Necroptosis|DNA Alkylator/Crosslinker|DNA Alkylation|ROS|MDM-2/p53
主要通路 DNA 损伤和修复
分子量 110.13
纯度 99.69%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
别名 DNAAlkylation|DNA alkylator|DNA Alkylation|Methyl methanesulfonate|甲磺酸甲酯

溶解度

DMSO:60 mg/mL (544.81 mM)

参考文献

1.D T Beranek. Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat Res. 1990 Jul;231(1):11-30.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2
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