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验证数据展示

  • WB analysis of L02 using 20720-1-AP (same clone as 20720-1-PBS)

    WB analysis of L02 using 20720-1-AP (same clone as 20720-1-PBS)

    L02 cells were subjected to SDS PAGE followed by western blot with 20720-1-AP (MYO7A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20720-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 20720-1-AP (same clone as 20720-1-PBS)

    IHC staining of human liver using 20720-1-AP (same clone as 20720-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 20720-1-AP (MYO7A antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20720-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MYO7A antibody included
  • IHC staining of human liver using 20720-1-AP (same clone as 20720-1-PBS)

    IHC staining of human liver using 20720-1-AP (same clone as 20720-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 20720-1-AP (MYO7A antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20720-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MYO7A antibody included
  • IHC staining of mouse skeletal muscle using 20720-1-AP (same clone as 20720-1-PBS)

    IHC staining of mouse skeletal muscle using 20720-1-AP (same clone as 20720-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 20720-1-AP (MYO7A antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20720-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MYO7A antibody included
  • IHC staining of mouse skeletal muscle using 20720-1-AP (same clone as 20720-1-PBS)

    IHC staining of mouse skeletal muscle using 20720-1-AP (same clone as 20720-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 20720-1-AP (MYO7A antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20720-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MYO7A antibody included
  • IF Staining of HepG2 using 20720-1-AP (same clone as 20720-1-PBS)

    IF Staining of HepG2 using 20720-1-AP (same clone as 20720-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using MYO7A antibody (20720-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 20720-1-PBS in a different storage buffer formulation.

MYO7A Polyclonal antibody, PBS Only

MYO7A Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 20720-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

DFNA11, DFNB2, myosin VIIA, MYOVIIA, MYU7A

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy MYO7A Ready-To-Use IHC Kit. MYO7A primary antibody included.

产品信息

20720-1-PBS targets MYO7A in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 myosin VIIA
别名 DFNA11, DFNB2, myosin VIIA, MYOVIIA, MYU7A
计算分子量 254 kDa
观测分子量240-250 kDa
GenBank蛋白编号NM_000260
基因名称 MYO7A
Gene ID (NCBI) 4647
RRIDAB_10734441
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ13402
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MYO7A, also named a USH1B, is one of myosins protein which are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, MYO7A might play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it might maintain the rigidity of stereocilia during the dynamic movements of the bundle. It is involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity. Defects in MYO7A are the cause of Usher syndrome type 1B (USH1B). Defects in MYO7A are the cause of deafness autosomal recessive type 2 (DFNB2). Defects in MYO7A are the cause of deafness autosomal dominant type 11 (DFNA11). The antibody is specific to MYO7A.

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