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验证数据展示

  • WB analysis using 19977-1-AP (same clone as 19977-1-PBS)

    WB analysis using 19977-1-AP (same clone as 19977-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 19977-1-AP (MYBPC3 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19977-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 19977-1-AP (same clone as 19977-1-PBS)

    IHC staining of mouse heart using 19977-1-AP (same clone as 19977-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 19977-1-AP (MYBPC3 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19977-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 19977-1-AP (same clone as 19977-1-PBS)

    IHC staining of mouse heart using 19977-1-AP (same clone as 19977-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 19977-1-AP (MYBPC3 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19977-1-PBS in a different storage buffer formulation.

MYBPC3 Polyclonal antibody, PBS Only

MYBPC3 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 19977-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

Cardiac MyBP C, Cardiac MyBP-C, C-protein, cardiac muscle isoform, MYBPC 3, Myosin-binding protein C, cardiac-type

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

19977-1-PBS targets MYBPC3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 myosin binding protein C, cardiac
别名 Cardiac MyBP C, Cardiac MyBP-C, C-protein, cardiac muscle isoform, MYBPC 3, Myosin-binding protein C, cardiac-type
计算分子量 141 kDa
观测分子量 141-150 kDa
GenBank蛋白编号NM_000256
基因名称 MYBPC3
Gene ID (NCBI) 4607
RRIDAB_10858232
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ14896
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MYBPC3 belongs to the immunoglobulin superfamily and MyBP family. MYBPC3 located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Defects in MYBPC3 are the cause of cardiomyopathy familial hypertrophic type 4 (CMH4). The antibody detects the full length form and the degradation bands around 28-54 kDa in SDS-PAGE.(PMID: 22076249)

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