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验证数据展示

  • WB analysis of HeLa using 67312-1-Ig (same clone as 67312-1-PBS)

    WB analysis of HeLa using 67312-1-Ig (same clone as 67312-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 67312-1-Ig (MTMR2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67312-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 67312-1-Ig (same clone as 67312-1-PBS)

    WB analysis of HeLa using 67312-1-Ig (same clone as 67312-1-PBS)

    WB result of MTMR2 antibody (67312-1-Ig; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-MTMR2 transfected HeLa cells. This data was developed using the same antibody clone with 67312-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

MTMR2 Monoclonal antibody, PBS Only

MTMR2 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67312-1-PBS

产品说明书

CloneNo. 1B11B7

宿主/亚型

Mouse / IgG2b

种属反应性

Human, Pig

应用

WB, Indirect ELISA

别名

CMT4B, CMT4B1, KIAA1073, MTMR2, myotubularin related protein 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67312-1-PBS targets MTMR2 in WB, Indirect ELISA applications and shows reactivity with Human, Pig samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, Pig
免疫原 MTMR2 fusion protein Ag28413 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 myotubularin related protein 2
别名 CMT4B, CMT4B1, KIAA1073, MTMR2, myotubularin related protein 2
计算分子量 73 kDa
观测分子量 66-73 kDa
GenBank蛋白编号BC052990
基因名称 MTMR2
Gene ID (NCBI) 8898
RRIDAB_2882572
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ13614
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MTMR2(myotubularin-related protein 2) is also named as KIAA1073 and belongs to the non-receptor class myotubularin subfamily, which is characterized by the presence of a phosphatase domain. It may regulate vesicular trafficking in Schwann cells (PMID:17880751) and its reversible phosphorylation represents a critical mechanism for regulating the subcellular localization of MTMR2(PMID:21372139). MTMR2 is a 73 kDa protein in its monomeric form and exist as a dimer within cells and the protein re-localizes to membranes in hypo-osmotic settings(PMID:16399794). Defects in MTMR2 are the cause of Charcot-Marie-Tooth disease type 4B1 (CMT4B1). MTMR2 has two isofroms with the molecular mass of 73 and 66 kDa.