验证数据展示
产品信息
32122-1-PBS targets MTHFSD in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag37100 Product name: Recombinant human MTHFSD protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-200 aa of BC112059 Sequence: MEPRAVGVSKQDIREQIWGYMESQNLADFPRPVHHRIPNFKGSYLACQNIKDLDVFARTQEVKVDPDKPLEGVRLLVLQSKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNYSVPIGLDSRVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKETPVVTIVHDCQVVDIPEELVEEHDIT 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | methenyltetrahydrofolate synthetase domain containing |
| 别名 | |
| 观测分子量 | 45 kDa |
| GenBank蛋白编号 | BC112059 |
| 基因名称 | MTHFSD |
| Gene ID (NCBI) | 64779 |
| RRID | AB_3670199 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q2M296 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MTHFSD is an RNA-binding protein that contains a methyltetrahydrofolate synthase structural domain and an RRM structural domain. In healthy motor neurons, MTHFSD is predominantly located in the nucleus, and studies have shown that MTHFSD, as a novel marker of stress granules, may be associated with aggregated proteins involved in amyotrophic lateral sclerosis (ALS).
