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验证数据展示

  • WB analysis using 23601-1-AP (same clone as 23601-1-PBS)

    WB analysis using 23601-1-AP (same clone as 23601-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23601-1-AP (MSL2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23601-1-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 23601-1-AP (same clone as 23601-1-PBS)

    IF Staining of A431 using 23601-1-AP (same clone as 23601-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using MSL2 antibody (23601-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-phalloidin (red). This data was developed using the same antibody clone with 23601-1-PBS in a different storage buffer formulation.

MSL2 Polyclonal antibody, PBS Only

MSL2 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 23601-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

别名

MS L2, MSL 2, MSL2 like 1, MSL2L1, RNF184

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

23601-1-PBS targets MSL2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag18727

Product name: Recombinant human MSL2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 228-577 aa of BC093790

Sequence: TEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 male-specific lethal 2 homolog (Drosophila)
别名 MS L2, MSL 2, MSL2 like 1, MSL2L1, RNF184
计算分子量 577 aa, 63 kDa
观测分子量70-75 kDa
GenBank蛋白编号BC093790
基因名称 MSL2
Gene ID (NCBI) 55167
RRIDAB_3742087
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen Affinity purified
UNIPROT IDQ9HCI7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

In mammals, MSL2 participates in histone H2B ubiquitination (H2Bub1) via the MSL complex, regulating transcription and chromatin remodeling. It is essential for embryonic development and has been implicated in cancer progression. MSL2's dysfunction is linked to developmental defects and oncogenesis, highlighting its critical role in gene regulation. (PMID: 30669413; PMID: 34899909)

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