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Species Reactivity
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • WB analysis using 67228-1-Ig (same clone as 67228-1-PBS)

    WB analysis using 67228-1-Ig (same clone as 67228-1-PBS)

    Non-boil and boiled HepG2 and A549 cell lysates were subjected to SDS PAGE followed by western blot with 67228-1-Ig (ABCC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. Left panel was exposed for 20 sec. and right panel was exposed for 1 min. This data was developed using the same antibody clone with 67228-1-PBS in a different storage buffer formulation.

  • IF Staining of A549 using 67228-1-Ig (same clone as 67228-1-PBS)

    IF Staining of A549 using 67228-1-Ig (same clone as 67228-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A549 cells using MRP1 antibody (67228-1-Ig, Clone: 1G4A2 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67228-1-PBS in a different storage buffer formulation.

MRP1 Monoclonal antibody, PBS Only

MRP1 Monoclonal Antibody for WB, IF/ICC, ELISA
Cat No. 67228-1-PBS

产品说明书

CloneNo. 1G4A2

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IF/ICC, ELISA

别名

ABCC1, MRP1/ABCC1, 1G4A2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67228-1-PBS targets MRP1 in WB, IF/ICC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, ELISA Application Description
经测试反应性 human
免疫原 MRP1 fusion protein Ag27048 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
别名 ABCC1, MRP1/ABCC1, 1G4A2
计算分子量 172 kDa
观测分子量 180-190 kDa
GenBank蛋白编号NM_004996
基因名称 MRP1
Gene ID (NCBI) 4363
RRIDAB_2882516
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP33527
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Multidrug resistant-associated protein 1 (MRP1; ABCC1) is a member of the ATP-binding cassette (ABC) transporter protein superfamily, subfamily C. MRP1 is overexpressed in cancers and contributes to the occurrence of multidrug resistance (MDR). Expression of MRP1 has been considered as a negative marker for the outcome of chemotherapy. Recently MRP1 has been reported to play a crucial role in Aβ clearance at the blood-brain barrier.