MRP1 Monoclonal antibody
MRP1 Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human and More (2)
Applications
WB, ELISA and More (1)
Conjugate
Unconjugated
CloneNo.
1G4A2
验证数据展示
经过测试的应用
Positive WB detected in | HepG2 cells |
推荐稀释比
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:5000-1:50000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
WB | See 11 publications below |
IHC | See 2 publications below |
产品信息
67228-1-Ig targets MRP1 in WB, IHC, ELISA applications and shows reactivity with Human samples.
Tested Applications | WB, ELISA |
Cited Applications | WB, IHC |
Tested Reactivity | Human |
Cited Reactivity | human, mouse |
Immunogen | MRP1 fusion protein Ag27048 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
Synonyms | ABC29, ABCC, ABCC1, Leukotriene C(4) transporter, LTC4 transporter, MRP, MRP1 |
Calculated Molecular Weight | 172 kDa |
Observed Molecular Weight | 180-190 kDa |
GenBank Accession Number | NM_004996 |
Gene Symbol | ABCC1 |
Gene ID (NCBI) | 4363 |
RRID | AB_2882516 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P33527 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Multidrug resistant-associated protein 1 (MRP1; ABCC1) is a member of the ATP-binding cassette (ABC) transporter protein superfamily, subfamily C. MRP1 is overexpressed in cancers and contributes to the occurrence of multidrug resistance (MDR). Expression of MRP1 has been considered as a negative marker for the outcome of chemotherapy. Recently MRP1 has been reported to play a crucial role in Aβ clearance at the blood-brain barrier.
实验方案
Product Specific Protocols | |
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WB protocol for MRP1 antibody 67228-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Environ Pollut Biotransformation of graphene oxide within lung fluids could intensify its synergistic biotoxicity effect with cadmium by inhibiting cellular efflux of cadmium. | ||
Cancers (Basel) NCAPG2 Maintains Cancer Stemness and Promotes Erlotinib Resistance in Lung Adenocarcinoma | ||
Front Cell Dev Biol Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway. | ||
Transl Oncol Pan-cancer analysis of ABCC1 as a potential prognostic and immunological biomarker | ||