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验证数据展示

  • IHC staining of mouse colon using 20890-1-AP (same clone as 20890-1-PBS)

    IHC staining of mouse colon using 20890-1-AP (same clone as 20890-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 20890-1-AP (METT11D1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20890-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse colon using 20890-1-AP (same clone as 20890-1-PBS)

    IHC staining of mouse colon using 20890-1-AP (same clone as 20890-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 20890-1-AP (METT11D1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20890-1-PBS in a different storage buffer formulation.

METTL17 Polyclonal antibody, PBS Only

METTL17 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 20890-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

METT11D1, False p73 target gene protein, Methyltransferase 11 domain-containing protein 1, Methyltransferase-like protein 17, Ribosome assembly protein METTL17, mitochondrial

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

20890-1-PBS targets METTL17 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag14518

Product name: Recombinant human METT11D1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-351 aa of BC005053

Sequence: MAAALKCLLTLGRWCPGLGVAPQARALAALVPGVTQVDNKSGFLQKRPHRQHPGILKLPHVRLPQALANGAQLLLLGSAGPTMENQVQTLTSYLWSRHLPVEPEELQRRARHLEKKFLENPDLSQTEEKLRGAVLHALRKTTYHWQELSYTEGLSLVYMAARLDGGFAAVSRAFHEIRARNPAFQPQTLMDFGSGTGSVTWAAHSIWGQSLREYMCVDRSAAMLVLAEKLLKGGSESGEPYIPGVFFRQFLPVSPKVQFDVVVSAFSLSELPSKADRTEVVQTLWRKTGHFLVLVENGTKAGHSLLMDARDLVLKGKEKSPLDPRPGFVFAPCPHELPCPQLTNLACSFSQ

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 methyltransferase 11 domain containing 1
别名 METT11D1, False p73 target gene protein, Methyltransferase 11 domain-containing protein 1, Methyltransferase-like protein 17, Ribosome assembly protein METTL17, mitochondrial
计算分子量 478 aa, 53 kDa
GenBank蛋白编号BC005053
基因名称 METT11D1
Gene ID (NCBI) 64745
RRIDAB_3742007
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H7H0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

METTL17 is located in mitochondria through its N-terminal targeting sequence and specifically interacts with 12S mitochondrial ribosomal RNA (mt-rRNA) as well as small subunits of mitochondrial ribosome (MSSUs). METTL17, a regulator of mitochondrial ribosomal RNA modifications, is required for the translation of mitochondrial coding genes. (PMID: 38377789, PMID: 31487196)

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